CLIPPERS SYNDROME – MRI FEATURES AND DIAGNOSTIC IMAGING FOLLOW-UP IN A PATIENT – CASE DISCUSSION AND REVIEW OF THE LITERATURE

Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) syndrome is a rare neurological disorder uncertain etiology, pathogenesis and clinical course. Pittock et al. in 2010 first described this chronic inflammatory neurologic condition, which preferably affects the brainstem. There an infiltration cells of affected regions typical dotted curvilinear contrast-enhancement zones on magnetic resonance imaging (MRI), including leptomeninges. I present one case 41-year-old male gradual onset suspected infectious disease worsening MRI features, biopsy confirmed diagnosis follow-up for 15 months. The findings evolution can narrow differential-diagnostic spectrum such case.